Lecture 2: Building and Grand Scale Engineering of Eukaryotic Viral Genomes and Chromosomes
Over the last 5 years, the JCVI Synthetic Biology team, which is best known for construction of bacterial cells programmed with synthetic genomes, has also... Read More
Lecture 1: Design, Construction, and Analysis of a Synthetic Minimal Bacterial Cell
The minimal cell is the hydrogen atom of cellular biology. Such a cell, because of its simplicity and absence of redundancy would be a platform... Read More
Lecture 2: Split Inteins as Synthetic Biology Tool to Control Biological Processes
Biological processes are carried out by complex networks of interacting proteins that continuously adapt to cellular environment and external stimuli with structural changes, which lead... Read More
Lecture 1: Optogenetic Control of Protein Nuclear Trafficking
Intracellular processes are controlled in many ways. One way consists in placing proteins in the right place at the right time. For instance, transcription factors... Read More
Lecture 2: SCRaMbLEing the Synthetic Yeast Genome
This lecture we will focus on the SCRaMbLE (Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution) method to evolve the synthetic yeast strains for novel... Read More
Lecture 1: Design and Construction of Synthetic Yeast Chromosomes
In this lecture, I will discuss the design principles of the synthetic yeast genome, and approaches to construct the synthetic chromosomes including methods to debug... Read More